Bumper sticker of the day: "Why is 'abbreviation' such a long word?"

Review of Lecture 18: Creative self expression: Gene Expression.

1. DNA --> RNA --> protein; base pairing.

2. Gene = DNA sequence on chromosome. Read in 5' to 3' direction. Promoter is upstream of start codon (5' end; not translated). Terminator is downstream of stop codon (3' end; not translated).

3. Gene expression tightly regulated. Some genes expressed only once during development; others expressed continuously (housekeeping genes); some switched on and off on a regular basis.

4. Prokaryotes control gene expression at transcriptional level; activator protein; repressor protein; operon.

5. Eukaryotes more complex because of compartments formed by membrane-bound organelles and differentiation; signaling (hormones); transcriptional, transport, translational, post-translational controls; totipotency.

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Last updated May 14, 1997.